Guillen seeking more consistency from Hanley  —  MIAMI — A look at Hanley Ramirez's averages at home and on the road reflect the inconsistencies the third baseman has gone through.  —  At Marlins Park, Ramirez is batting .309 with five home runs and 20 RBIs.  On the road, he's hitting .195 with six home runs and 17 RBIs.

Matt Cain throws perfect game, strikes out 14 as Giants drub Astros  —  SAN FRANCISCO — Matt Cain pitched the 22nd perfect game in major league history and first for the Giants, striking out a career-high 14 and getting help from two spectacular catches to beat the Houston Astros 10-0 on Wednesday night.

Royals beat Brewers on bases-loaded walk in 11th  —  KANSAS CITY, Mo.—Mike Moustakas walked with the bases loaded in the 11th inning Wednesday night, giving the Kansas City Royals a come-from-behind 4-3 victory over the Milwaukee Brewers.  —  Billy Butler singled to lead off the inning against Kameron Loe …

Inge Had Go-Ahead Double, Lifts A's Past Rockies  —  DENVER (AP) — Brandon Inge hit a go-ahead two-run double during a three-run ninth inning, and the Oakland Athletics rallied to beat the Colorado Rockies 10-8 Wednesday night.  —  Todd Helton hit a grand slam and Michael Cuddyer had two homers …

Thome Powers Hamels, Phillies Past Twins 9-8  —  MINNEAPOLIS (AP) — Jim Thome drove in four runs against his former team, including a long homer to pad Philadelphia's lead, and the Phillies hung on for a 9-8 victory over the Minnesota Twins on Wednesday night.

Final Score: Mets 9 Rays 1  —  The Mets (34-29) defeated the Rays (35-27) tonight by the score of 9-1 in Tampa tonight.  —  The Least You Should Know: … The Elias Sports Bureau reports that Tom Glavine in 2006 is the only other Mets pitcher to be the first major league pitcher to reach 10 wins in a season.

Strasburg shuts down Blue Jays, improves to 8-1  —  TORONTO (AP) — Stephen Strasburg won his fifth straight start, Tyler Moore hit the first two home runs of his career and the Washington Nationals beat the Toronto Blue Jays 6-2 Wednesday to complete a three-game sweep.

Phillips Leads Reds Past Indians 5-3  —  CINCINNATI (AP) — Brandon Phillips helped the Cincinnati Reds get through their illness with another strong game against his former team, hitting a two-run homer and driving in three runs in a 5-3 victory over the Cleveland Indians on Wednesday night.

Lance Lynn Wins 10th, Cardinals Edge White Sox 1-0  —  ST. LOUIS (AP) — Lance Lynn struck out a career-high 12 to stay tied for the major league lead in wins and Carlos Beltran hit his NL-best 19th home run Wednesday night, sending the St. Louis Cardinals to a 1- victory over the White Sox …

Aybar, Callaspo homer to lead Angels over Dodgers  —  LOS ANGELES—Erick Aybar led off the ninth inning with his first home run of the season, Alberto Callaspo also went deep and the Los Angeles Angels beat the Dodgers 2-1 Wednesday night in the rubber game of the season's first Freeway Series.

Amid trade rumors, Dempster talks with Epstein  —  CHICAGO — Ryan Dempster, the subject of trade talks, had a long chat with Theo Epstein, Cubs president of baseball operations, in the stands at Wrigley Field before Wednesday's game.  —  The topic?  Dempster told MLB.com they were talking …

Epstein admits to errors late in Red Sox tenure  —  While he was adamant that he was proud of his overall body of work with the team, former Boston Red Sox general manager Theo Epstein acknowledged Wednesday that late in his tenure he veered from the philosophy of patience he helped to instill in order to try to win immediately.

White Sox agree to deal with top pick Hawkins  —  ST. LOUIS — Courtney Hawkins, who was taken with the 13th overall selection in the 2012 First-Year Player Draft, has agreed to terms with the White Sox, as confirmed by two sources to MLB.com.  —  The 18-year-old from Carroll High School in Corpus Christi …